2M3O

Structure and dynamics of a human Nedd4 WW domain-ENaC complex

Summary for 2M3O

• Entry DOI: 10.2210/pdb2m3o/pdb
• Related: 1I5H 2EZ5
• NMR Information: BMRB: 18971
• Descriptor: E3 ubiquitin-protein ligase NEDD4, Amiloride-sensitive sodium channel subunit alpha (2 entities in total)
• Functional Keywords: ww domain, enac, ubiquitin e3 ligase, peptide binding protein-protein binding complex, peptide binding protein/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): P46934; Apical cell membrane; Multi-pass membrane protein: P37088
• Total number of polymer chains: 2
• Total formula weight: 6029.79

Authors

Bobby, R.,Medini, K.,Neudecker, P.,Lee, V.,MacDonald, F.J.,Brimble, M.A.,Lott, J.,Dingley, A.J. (deposition date: 2013-01-23, release date: 2013-08-28)

• Primary citation: Bobby, R.,Medini, K.,Neudecker, P.,Lee, T.V.,Brimble, M.A.,McDonald, F.J.,Lott, J.S.,Dingley, A.J.; Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif.; Biochim.Biophys.Acta, 1834:1632-1641, 2013; PubMed: 23665454; DOI: 10.1016/j.bbapap.2013.04.031

Experimental method

SOLUTION NMR