2M3O
Structure and dynamics of a human Nedd4 WW domain-ENaC complex
Functional Information from PROSITE/UniProt
| site_id | PS01159 |
| Number of Residues | 26 |
| Details | WW_DOMAIN_1 WW/rsp5/WWP domain signature. Wevrhapngrp.FFidhntktTTWEDP |
| Chain | Residue | Details |
| W | TRP427-PRO452 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 33 |
| Details | Domain: {"description":"WW 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00224","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"PY motif; recruits WW domain-containing proteins and is thereby required for ubiquitination and inhibition of the channel by NEDD4 and NEDD4L","evidences":[{"source":"PubMed","id":"17502380","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23665454","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
