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2M3O

Structure and dynamics of a human Nedd4 WW domain-ENaC complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1WE3 ubiquitin-protein ligase NEDD4polymer434971.61UniProt (P46934)
Pfam (PF00397)
In PDB
Homo sapiens (human)Cell proliferation-inducing gene 53 protein, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4
2PAmiloride-sensitive sodium channel subunit alphapolymer111058.21UniProt (P37088)
In PDB
Homo sapiensAlpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, ENaCA, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA
Sequence modifications
W: 419 - 458 (UniProt: P46934)
PDBExternal DatabaseDetails
Gly 416-expression tag
Ser 417-expression tag
Met 418-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight6029.8
All*Total formula weight6029.8
*Water molecules are not included.

225158

PDB entries from 2024-09-18

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