2J8L
FXI Apple 4 domain loop-out conformation
Summary for 2J8L
Entry DOI | 10.2210/pdb2j8l/pdb |
Related | 1XX9 1XXD 1XXF 1ZHM 1ZHP 1ZHR 1ZJD 1ZLR 1ZMJ 1ZML 1ZMN 1ZOM 1ZPZ 1ZRK 1ZSJ 1ZSK 1ZSL 1ZTJ 1ZTK 1ZTL 2J8J |
Descriptor | COAGULATION FACTOR XI (1 entity in total) |
Functional Keywords | protease, hydrolase, glycoprotein, polymorphism, serine protease, heparin-binding, disease mutation, fxi / blood coagulation / pan domain /apple domain / blood coagulation, alternative splicing |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P03951 |
Total number of polymer chains | 2 |
Total formula weight | 19916.55 |
Authors | Samuel, D.,Cheng, H.,Riley, P.W.,Canutescu, A.A.,Bu, Z.,Walsh, P.N.,Roder, H. (deposition date: 2006-10-25, release date: 2007-10-02, Last modification date: 2011-07-13) |
Primary citation | Samuel, D.,Cheng, H.,Riley, P.W.,Canutescu, A.A.,Nagaswami, C.,Weisel, J.W.,Bu, Z.,Walsh, P.N.,Roder, H. Solution Structure of the A4 Domain of Factor Xi Sheds Light on the Mechanism of Zymogen Activation. Proc.Natl.Acad.Sci.USA, 104:15693-, 2007 Cited by PubMed: 17884987DOI: 10.1073/PNAS.0703080104 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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