2J2S
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase
Summary for 2J2S
Entry DOI | 10.2210/pdb2j2s/pdb |
Related | 2AGH |
Descriptor | ZINC FINGER PROTEIN HRX, ZINC ION (2 entities in total) |
Functional Keywords | transcription regulation, chromosomal rearrangement, zinc-finger, dna-binding, bromodomain, polymorphism, mixed lineage leukaemia, zinc binding, transcription, metal-binding, zinc, cxxc, mbd1, hox genes, chromatin, methylation, proto-oncogene, nuclear protein, phosphorylation, cpg dinucleotide, alternative splicing |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164 |
Total number of polymer chains | 1 |
Total formula weight | 8197.48 |
Authors | Allen, M.D.,Grummitt, C.G.,Hilcenko, C.,Young-Min, S.,Tonkin, L.M.,Johnson, C.M.,Bycroft, M.,Warren, A.J. (deposition date: 2006-08-17, release date: 2006-08-21, Last modification date: 2024-05-15) |
Primary citation | Allen, M.D.,Grummitt, C.G.,Hilcenko, C.,Min, S.Y.,Tonkin, L.M.,Johnson, C.M.,Freund, S.M.,Bycroft, M.,Warren, A.J. Solution Structure of the Nonmethyl-Cpg-Binding Cxxc Domain of the Leukaemia-Associated Mll Histone Methyltransferase Embo J., 25:4503-, 2006 Cited by PubMed: 16990798DOI: 10.1038/SJ.EMBOJ.7601340 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report