2J2S
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ZINC FINGER PROTEIN HRX | polymer | 72 | 8066.7 | 1 | UniProt (Q03164) Pfam (PF02008) | HOMO SAPIENS (HUMAN) | ALL-1, TRITHORAX-LIKE PROTEIN, CXXC DOMAIN OF MLL-1 |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1143 - 1214 (UniProt: Q03164)
| PDB | External Database | Details |
|---|---|---|
| Gly 1143 | Glu 1143 | engineered mutation |
| Gly 1144 | Pro 1144 | engineered mutation |
| Ser 1145 | Pro 1145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8066.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 8197.5 |
