2J2S
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A2215 |
| Chain | Residue |
| A | CYS1167 |
| A | CYS1170 |
| A | CYS1173 |
| A | CYS1189 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A2216 |
| Chain | Residue |
| A | ASN1196 |
| A | CYS1155 |
| A | GLY1156 |
| A | CYS1158 |
| A | CYS1161 |
| A | CYS1194 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | ZN_FING: CXXC-type => ECO:0000255|PROSITE-ProRule:PRU00509, ECO:0000269|PubMed:29276034 |
| Chain | Residue | Details |
| A | LYS1147-GLN1195 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00509, ECO:0000269|PubMed:29276034, ECO:0007744|PDB:4NW3 |
| Chain | Residue | Details |
| A | CYS1155 | |
| A | CYS1158 | |
| A | CYS1161 | |
| A | CYS1167 | |
| A | CYS1170 | |
| A | CYS1173 | |
| A | CYS1189 | |
| A | CYS1194 |
