2AGH

Structural basis for cooperative transcription factor binding to the CBP coactivator

Summary for 2AGH

• Entry DOI: 10.2210/pdb2agh/pdb
• NMR Information: BMRB: 6750
• Descriptor: Myb proto-oncogene protein, Crebbp protein, Zinc finger protein HRX (3 entities in total)
• Functional Keywords: transcription
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: P06876; Cytoplasm (By similarity): P45481; Nucleus. MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164
• Total number of polymer chains: 3
• Total formula weight: 16610.94

Authors

De Guzman, R.N.,Goto, N.K.,Dyson, H.J.,Wright, P.E. (deposition date: 2005-07-26, release date: 2005-11-22, Last modification date: 2021-07-07)

• Primary citation: De Guzman, R.N.,Goto, N.K.,Dyson, H.J.,Wright, P.E.; Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator; J.Mol.Biol., 355:1005-1013, 2006; PubMed: 16253272; DOI: 10.1016/j.jmb.2005.09.059

Experimental method

SOLUTION NMR