2GVD

Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With TNP-ATP and Mn

Summary for 2GVD

• Entry DOI: 10.2210/pdb2gvd/pdb
• Related: 1TL7 1U0H
• Descriptor: Adenylate cyclase type 5, Adenylate cyclase type 2, Guanine nucleotide-binding protein G(s), alpha subunit, ... (9 entities in total)
• Functional Keywords: adenylyl cyclase, gsa, tnp-atp, lyase
• Biological source: Canis lupus familiaris (dog); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : P30803; Membrane ; Multi-pass membrane protein : P26769; Cell membrane ; Lipid-anchor : P04896
• Total number of polymer chains: 3
• Total formula weight: 97021.58

Authors

Mou, T.-C.,Sprang, S.R. (deposition date: 2006-05-02, release date: 2006-07-04, Last modification date: 2023-08-30)

• Primary citation: Mou, T.-C.,Gille, A.,Suryanarayana, S.,Richter, M.,Seifert, R.,Sprang, S.R.; Broad specificity of Mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.; Mol.Pharmacol., 70:878-886, 2006; PubMed: 16766715; DOI: 10.1124/mol.106.026427

Experimental method

X-RAY DIFFRACTION (2.9 Å)