2G1T

A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain

Summary for 2G1T

• Entry DOI: 10.2210/pdb2g1t/pdb
• Descriptor: Proto-oncogene tyrosine-protein kinase ABL1, ATP-Peptide Conjugate, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: kinase, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
• Total number of polymer chains: 8
• Total formula weight: 141424.99

Authors

Levinson, N.M.,Kuchment, O. (deposition date: 2006-02-14, release date: 2006-05-23, Last modification date: 2023-08-30)

• Primary citation: Levinson, N.M.,Kuchment, O.,Shen, K.,Young, M.A.,Koldobskiy, M.,Karplus, M.,Cole, P.A.,Kuriyan, J.; A SRC-like inactive conformation in the abl tyrosine kinase domain.; Plos Biol., 4:753-767, 2006; PubMed: 16640460; DOI: 10.1371/journal.pbio.0040144

Experimental method

X-RAY DIFFRACTION (1.8 Å)