2G1T
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 287 | 33223.0 | 4 | UniProt (P00519) Pfam (PF07714) | Homo sapiens (human) | p150, c- ABL, Abelson murine leukemia viral oncogene homolog 1 |
| 2 | E, F, G, H (E, F, G, H) | ATP-Peptide Conjugate | polymer | 13 | 1528.7 | 4 | |||
| 3 | I, J, K, L (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | M, N, O, P (E, F, G, H) | THIOPHOSPHORIC ACID O-((ADENOSYL-PHOSPHO)PHOSPHO)-S-ACETAMIDYL-DIESTER | non-polymer | 580.3 | 4 | Chemie (112) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 899 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 229 - 512 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Gly 226 | - | cloning artifact |
| His 227 | - | cloning artifact |
| Met 228 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 139006.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2418.4 | |
| All* | Total formula weight | 141425.0 |
