2DSQ
Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Summary for 2DSQ
Entry DOI | 10.2210/pdb2dsq/pdb |
Related | 1WQJ 2DSP 2DSR |
Descriptor | Insulin-like growth factor-binding protein 4, Insulin-like growth factor IB, Insulin-like growth factor-binding protein 1 (3 entities in total) |
Functional Keywords | igf, igfbp, insulin, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P22692 P05019 P08833 |
Total number of polymer chains | 6 |
Total formula weight | 56737.09 |
Authors | Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. (deposition date: 2006-07-05, release date: 2006-08-22, Last modification date: 2024-10-16) |
Primary citation | Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103:13028-13033, 2006 Cited by PubMed: 16924115DOI: 10.1073/pnas.0605652103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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