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2DSQ

Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(B, A)
Insulin-like growth factor-binding protein 4polymer929826.52UniProt (P22692)
Pfam (PF00219)
Homo sapiens (human)IGFBP-4, IBP-4, IGF-binding protein 4
2B, D
(I, C)
Insulin-like growth factor IBpolymer707663.82UniProt (P05019)
Pfam (PF00049)
Homo sapiens (human)IGF-IB, Somatomedin C, Mechano growth factor, MGF
3E, F
(G, H)
Insulin-like growth factor-binding protein 1polymer9410878.32UniProt (P08833)
Pfam (PF00086)
Homo sapiens (human)IGFBP-1, IBP-1, IGF-binding protein 1, Placental protein 12, PP12
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight56737.1
All*Total formula weight56737.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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