2CJX

Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis

Summary for 2CJX

• Entry DOI: 10.2210/pdb2cjx/pdb
• Related: 1CP3 1GFW 1I3O 1NME 1NMQ 1NMS 1PAU 1QX3 1RE1 1RHJ 1RHK 1RHM 1RHQ 1RHR 1RHU 2C1E 2C2K 2C2M 2C2O 2CDR 2CJY
• Related PRD ID: PRD_000277
• Descriptor: CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE, ... (4 entities in total)
• Functional Keywords: protease, apoptosis, cysteine protease, thiol protease, ice, clan cd, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P42574 P42574
• Total number of polymer chains: 3
• Total formula weight: 29239.06

Authors

Ganesan, R.,Mittl, P.R.E.,Jelakovic, S.,Grutter, M.G. (deposition date: 2006-04-09, release date: 2006-06-27, Last modification date: 2017-06-28)

• Primary citation: Ganesan, R.,Mittl, P.R.E.,Jelakovic, S.,Grutter, M.G.; Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis; J.Mol.Biol., 359:1378-, 2006; PubMed: 16787777; DOI: 10.1016/J.JMB.2006.04.051

Experimental method

X-RAY DIFFRACTION (1.7 Å)