2BBT
Human deltaF508 NBD1 with two solublizing mutations.
Summary for 2BBT
Entry DOI | 10.2210/pdb2bbt/pdb |
Related | 2BBO 2BBS |
Descriptor | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | atp binding cassette, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65950.67 |
Authors | Lewis, H.A.,Kearins, M.C.,Conners, K.,Zhao, X.,Lu, F.,Sauder, J.M.,Emtage, S. (deposition date: 2005-10-17, release date: 2005-11-01, Last modification date: 2023-08-23) |
Primary citation | Lewis, H.A.,Wang, C.,Zhao, X.,Hamuro, Y.,Conners, K.,Kearins, M.C.,Lu, F.,Sauder, J.M.,Molnar, K.S.,Coales, S.J.,Maloney, P.C.,Guggino, W.B.,Wetmore, D.R.,Weber, P.C.,Hunt, J.F. Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry. J.Mol.Biol., 396:406-430, 2010 Cited by PubMed: 19944699DOI: 10.1016/j.jmb.2009.11.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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