2BBS

Human deltaF508 NBD1 with three solubilizing mutations

Summary for 2BBS

Entry DOI	10.2210/pdb2bbs/pdb
Related	2BBO 2BBT
Descriptor	Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	atp binding cassette, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	65830.48
Authors	Lewis, H.A.,Kearins, M.C.,Conners, K.,Zhao, X.,Lu, F.,Sauder, J.M.,Emtage, S. (deposition date: 2005-10-17, release date: 2005-11-01, Last modification date: 2023-08-23)
Primary citation	Lewis, H.A.,Wang, C.,Zhao, X.,Hamuro, Y.,Conners, K.,Kearins, M.C.,Lu, F.,Sauder, J.M.,Molnar, K.S.,Coales, S.J.,Maloney, P.C.,Guggino, W.B.,Wetmore, D.R.,Weber, P.C.,Hunt, J.F. Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry. J.Mol.Biol., 396:406-430, 2010 Cited by PubMed: 19944699 DOI: 10.1016/j.jmb.2009.11.051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation