2AZE

Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer

Summary for 2AZE

Entry DOI	10.2210/pdb2aze/pdb
Descriptor	Transcription factor Dp-1, Transcription factor E2F1, Retinoblastoma-associated protein, ... (4 entities in total)
Functional Keywords	coiled coil, beta sandwich, cell cycle, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q14186 Q01094 P06400
Total number of polymer chains	3
Total formula weight	34616.36
Authors	Rubin, S.M.,Gall, A.L.,Zheng, N.,Pavletich, N.P. (deposition date: 2005-09-10, release date: 2006-01-31, Last modification date: 2024-02-14)
Primary citation	Rubin, S.M.,Gall, A.L.,Zheng, N.,Pavletich, N.P. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell(Cambridge,Mass.), 123:1093-1106, 2005 Cited by PubMed: 16360038 DOI: 10.1016/j.cell.2005.09.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation