2AZE
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transcription factor Dp-1 | polymer | 155 | 17603.1 | 1 | UniProt (Q14186) Pfam (PF08781) In PDB | Homo sapiens (human) | E2F dimerization partner 1, DRTF1-polypeptide-1, DRTF1 |
| 2 | B | Transcription factor E2F1 | polymer | 106 | 11898.4 | 1 | UniProt (Q01094) Pfam (PF16421) In PDB | Homo sapiens (human) | E2F-1, Retinoblastoma binding protein 3, RBBP-3, PRB-binding protein E2F-1, PBR3, Retinoblastoma-associated protein 1, RBAP-1 |
| 3 | C | Retinoblastoma-associated protein | polymer | 46 | 5114.9 | 1 | UniProt (P06400) In PDB | Homo sapiens (human) | PP110, P105-RB, RB |
| 4 | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 199 - 350 (UniProt: Q14186)
B: 200 - 301 (UniProt: Q01094)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | cloning artifact |
| Glu 197 | - | cloning artifact |
| Phe 198 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | cloning artifact |
| Ser 197 | - | cloning artifact |
| His 198 | - | cloning artifact |
| Met 199 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34616.4 | |
| All* | Total formula weight | 34616.4 |
