2AS5

Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.

2AS5 の概要

関連するPDBエントリー1a02 1owr 2a07
分子名称5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', Nuclear factor of activated T-cells, cytoplasmic 2, ... (6 entities in total)
機能のキーワードforkhead domain, rhr domain, rel homology region, ig fold, winged helix-turn-helix, b-dna, transcription-dna complex, transcription/dna
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cytoplasm Q13469
Nucleus (Probable) O15409
ポリマー鎖数8
分子量合計113024.94
構造登録者
Wu, Y.,Stroud, J.C.,Borde, M.,Bates, D.L.,Guo, L.,Han, A.,Rao, A.,Chen, L. (登録日: 2005-08-22, 公開日: 2006-08-08, 最終更新日: 2011-07-13)
主引用文献
Wu, Y.,Borde, M.,Heissmeyer, V.,Feuerer, M.,Lapan, A.D.,Stroud, J.C.,Bates, D.L.,Guo, L.,Han, A.,Ziegler, S.F.,Mathis, D.,Benoist, C.,Chen, L.,Rao, A.
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126:375-387, 2006
PubMed: 16873067 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.cell.2006.05.042
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.7 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.291284.6%3.8%5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード