2AS5
Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0043565 | molecular_function | sequence-specific DNA binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0043565 | molecular_function | sequence-specific DNA binding |
| M | 0003677 | molecular_function | DNA binding |
| M | 0003700 | molecular_function | DNA-binding transcription factor activity |
| M | 0006355 | biological_process | regulation of DNA-templated transcription |
| N | 0003677 | molecular_function | DNA binding |
| N | 0003700 | molecular_function | DNA-binding transcription factor activity |
| N | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG F 201 |
| Chain | Residue |
| F | LEU556 |
| F | SER557 |
| F | HIS559 |
| F | PHE562 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG G 202 |
| Chain | Residue |
| G | LEU556 |
| G | SER557 |
| G | HIS559 |
| G | PHE562 |
Functional Information from PROSITE/UniProt
| site_id | PS00658 |
| Number of Residues | 7 |
| Details | FORK_HEAD_2 Fork head domain signature 2. WKNAVRH |
| Chain | Residue | Details |
| F | TRP548-HIS554 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 364 |
| Details | Domain: {"description":"RHD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00265","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | DNA binding: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Nuclear localization signal"} |
| Chain | Residue | Details |
