2ARP
Activin A in complex with Fs12 fragment of follistatin
Summary for 2ARP
Entry DOI | 10.2210/pdb2arp/pdb |
Related | 2ARV |
Descriptor | Inhibin beta A chain, Follistatin, NICKEL (II) ION, ... (6 entities in total) |
Functional Keywords | cystine knot, disulfide rich, egf domain, kazal domain, protein complex, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P08476 P21674 |
Total number of polymer chains | 2 |
Total formula weight | 30381.82 |
Authors | Harrington, A.E.,Morris-Triggs, S.A.,Ruotolo, B.T.,Robinson, C.V.,Ohnuma, S.,Hyvonen, M. (deposition date: 2005-08-21, release date: 2006-03-07, Last modification date: 2023-08-23) |
Primary citation | Harrington, A.E.,Morris-Triggs, S.A.,Ruotolo, B.T.,Robinson, C.V.,Ohnuma, S.,Hyvonen, M. Structural basis for the inhibition of activin signalling by follistatin Embo J., 25:1035-1045, 2006 Cited by PubMed: 16482217DOI: 10.1038/sj.emboj.7601000 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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