2ARP
Activin A in complex with Fs12 fragment of follistatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Inhibin beta A chain | polymer | 116 | 12991.9 | 1 | UniProt (P08476) Pfam (PF00019) In PDB | Homo sapiens (human) | Activin beta-A chain, Erythroid differentiation protein, EDF |
| 2 | F | Follistatin | polymer | 152 | 16593.2 | 1 | UniProt (P21674) Pfam (PF09289) Pfam (PF07648) In PDB | Rattus norvegicus (Norway rat) | FS, Activin-binding protein |
| 3 | A | NICKEL (II) ION | non-polymer | 58.7 | 3 | Chemie (NI) | |||
| 4 | A | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | non-polymer | 252.3 | 1 | Chemie (1PG) | |||
| 5 | A, F | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
F: 64 - 212 (UniProt: P21674)
| PDB | External Database | Details |
|---|---|---|
| Gly 61 | - | cloning artifact |
| Ser 62 | - | cloning artifact |
| Met 63 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29585.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 796.8 | |
| All* | Total formula weight | 30381.8 |
