2A5F
Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6
Summary for 2A5F
Entry DOI | 10.2210/pdb2a5f/pdb |
Descriptor | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, MAGNESIUM ION, ... (8 entities in total) |
Functional Keywords | protein transport/transferase, protein transport-transferase complex |
Biological source | Homo sapiens (human) More |
Cellular location | Golgi apparatus: P62330 |
Total number of polymer chains | 2 |
Total formula weight | 43146.94 |
Authors | O'Neal, C.J.,Jobling, M.G.,Holmes, R.K.,Hol, W.G.J. (deposition date: 2005-06-30, release date: 2005-08-16, Last modification date: 2024-04-03) |
Primary citation | O'Neal, C.J.,Jobling, M.G.,Holmes, R.K.,Hol, W.G. Structural basis for the activation of cholera toxin by human ARF6-GTP. Science, 309:1093-1096, 2005 Cited by PubMed: 16099990DOI: 10.1126/science.1113398 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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