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2Z2D

Solution structure of human macrophage elastase (MMP-12) catalytic domain complexed with a gamma-keto butanoic acid inhibitor

Summary for 2Z2D
Entry DOI10.2210/pdb2z2d/pdb
Related1JIZ 1JK3 1RMZ 1ROS 1YCM 2OXU
DescriptorMacrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywordshuman macrophage elastase, complex, solution structure, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix (Probable): P39900
Total number of polymer chains1
Total formula weight18883.37
Authors
Zheng, X.,Ou, L. (deposition date: 2007-05-18, release date: 2007-11-20, Last modification date: 2022-03-16)
Primary citationZheng, X.,Ou, L.
Solution structure of human macrophage elastase (MMP-12) catalytic domain complexed with a gamma-keto butanoic acid inhibitor
To be published,
Experimental method
SOLUTION NMR
Structure validation

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