2Z2D
Solution structure of human macrophage elastase (MMP-12) catalytic domain complexed with a gamma-keto butanoic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Macrophage metalloelastase | polymer | 164 | 18235.4 | 1 | UniProt (P39900) Pfam (PF00413) In PDB | Homo sapiens (human) | HME, Matrix metalloproteinase-12, MMP-12, Macrophage elastase, ME |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | A | (3R)-3-{4-[(4-CHLOROPHENYL)ETHYNYL]BENZOYL}NONANOIC ACID | non-polymer | 396.9 | 1 | Chemie (HSI) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18235.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 648.0 | |
| All* | Total formula weight | 18883.4 |
