2VBL

Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers

Summary for 2VBL

• Entry DOI: 10.2210/pdb2vbl/pdb
• Related: 1AF5 1BP7 1G9Y 1G9Z 1MOW 1N3E 1N3F 1T9I 1T9J 1U0C 1U0D 2VBJ 2VBN 2VBO
• Descriptor: DNA ENDONUCLEASE I-CREI, 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', 5'-D(*DT*DT*DA*DG*DG*DA*DT*DC*DC*DT*DT*DC *DAP*DAP)-3', ... (8 entities in total)
• Functional Keywords: uv-induced dna damage, cutting dna endonucleases, plastid, nuclease, hydrolase, chloroplast, endonuclease, intron homing, amel3- 4_magnesium, double strand break (dsb), homing endonucleases (hes)
• Biological source: CHLAMYDOMONAS REINHARDTII; More
• Cellular location: Plastid, chloroplast: P05725 2VBL
• Total number of polymer chains: 6
• Total formula weight: 49829.09

Authors

Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Arnould, S.,Perez, C.,Cabaniols, J.P.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G. (deposition date: 2007-09-14, release date: 2008-10-28, Last modification date: 2023-12-13)

• Primary citation: Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Cabaniols, J.P.,Daboussi, F.,Arnould, S.,Perez, C.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G.; Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases; Nature, 456:107-, 2008; PubMed: 18987743; DOI: 10.1038/NATURE07343

Experimental method

X-RAY DIFFRACTION (1.8 Å)