2UXN
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
Summary for 2UXN
Entry DOI | 10.2210/pdb2uxn/pdb |
Related | 2B2T 2B2U 2B2V 2B2W 2C1J 2C1N 2COM 2CV5 2H94 2IW5 2UXX |
Descriptor | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, HISTONE H3.1, ... (7 entities in total) |
Functional Keywords | oxidoreductase-transcription regulator complex, oxidoreductase-repressor complex, histone demethylase, fad, lsd1, corest, repressor, transcription regulation, host-virus interaction, chromatin demethylation, nuclear protein, phosphorylation, chromatin regulator, nucleosomes, transcription, oxidoreductase, oxidoreductase/transcription regulator |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: O60341 Q9UKL0 P68431 |
Total number of polymer chains | 3 |
Total formula weight | 103819.83 |
Authors | Yang, M.,Culhane, J.C.,Szewczuk, L.M.,Gocke, C.B.,Brautigam, C.A.,Tomchick, D.R.,Machius, M.,Cole, P.A.,Yu, H. (deposition date: 2007-03-28, release date: 2007-05-29, Last modification date: 2011-07-13) |
Primary citation | Yang, M.,Culhane, J.C.,Szewczuk, L.M.,Gocke, C.B.,Brautigam, C.A.,Tomchick, D.R.,Machius, M.,Cole, P.A.,Yu, H. Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation. Nat.Struct.Mol.Biol., 14:535-, 2007 Cited by PubMed: 17529991DOI: 10.1038/NSMB1255 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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