2UXN
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 | polymer | 666 | 74126.8 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) In PDB | HOMO SAPIENS (HUMAN) | FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2, BRAF35-HDAC COMPLEX PROTEIN BHC110, LYSINE-SPECIFIC DEMETHYLASE 1 |
| 2 | B | REST COREPRESSOR 1 | polymer | 235 | 26425.7 | 1 | UniProt (Q9UKL0) Pfam (PF20878) Pfam (PF00249) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN COREST |
| 3 | E | HISTONE H3.1 | polymer | 21 | 2316.7 | 1 | UniProt (P68431) In PDB | HOMO SAPIENS | H3/A, H3/B, H3/C, H3/D, H3/F, H3/H, H3/I, H3/J, H3/K, H3/L |
| 4 | A | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | non-polymer | 787.6 | 1 | Chemie (FDA) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 102869.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 950.6 | |
| All* | Total formula weight | 103819.8 |
