2JJC
Hsp90 alpha ATPase domain with bound small molecule fragment
Summary for 2JJC
Entry DOI | 10.2210/pdb2jjc/pdb |
Related | 1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1YC1 1YC3 1YC4 2BSM 2BT0 2BUG 2BYH 2BYI 2BZ5 2C2L 2CCS 2CCT 2CCU 2CDD 2UWD 2VCI 2VCJ |
Descriptor | HEAT SHOCK PROTEIN HSP 90-ALPHA, DIMETHYL SULFOXIDE, PYRIMIDIN-2-AMINE, ... (4 entities in total) |
Functional Keywords | hsp90, atpase, chaperone, cytoplasm, heat shock, nucleotide-binding, alternative splicing, atp-binding, phosphoprotein, stress response |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : P07900 |
Total number of polymer chains | 1 |
Total formula weight | 24579.80 |
Authors | Congreve, M.,Chessari, G.,Tisi, D.,Woodhead, A.J. (deposition date: 2008-03-31, release date: 2008-07-15, Last modification date: 2023-12-13) |
Primary citation | Congreve, M.,Chessari, G.,Tisi, D.,Woodhead, A.J. Recent Developments in Fragment-Based Drug Discovery. J.Med.Chem., 51:3661-, 2008 Cited by PubMed: 18457385DOI: 10.1021/JM8000373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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