1OSF
Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin
Summary for 1OSF
Entry DOI | 10.2210/pdb1osf/pdb |
Descriptor | heat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alpha, 17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | cell cycle |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P07900 |
Total number of polymer chains | 1 |
Total formula weight | 25095.40 |
Authors | Jez, J.M.,Chen, J.C.-H.,Rastelli, G.,Stroud, R.M.,Santi, D.V. (deposition date: 2003-03-19, release date: 2003-05-27, Last modification date: 2024-02-14) |
Primary citation | Jez, J.M.,Chen, J.C.,Rastelli, G.,Stroud, R.M.,Santi, D.V. Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90 Chem.Biol., 10:361-368, 2003 Cited by PubMed: 12725864DOI: 10.1016/S1074-5521(03)00075-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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