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1OSF

Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin

Summary for 1OSF
Entry DOI10.2210/pdb1osf/pdb
Descriptorheat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alpha, 17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
Functional Keywordscell cycle
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P07900
Total number of polymer chains1
Total formula weight25095.40
Authors
Jez, J.M.,Chen, J.C.-H.,Rastelli, G.,Stroud, R.M.,Santi, D.V. (deposition date: 2003-03-19, release date: 2003-05-27, Last modification date: 2024-02-14)
Primary citationJez, J.M.,Chen, J.C.,Rastelli, G.,Stroud, R.M.,Santi, D.V.
Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90
Chem.Biol., 10:361-368, 2003
Cited by
PubMed: 12725864
DOI: 10.1016/S1074-5521(03)00075-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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