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1OSF

Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
heat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alphapolymer21524122.21UniProt (P07900)
Pfam (PF13589)
Homo sapiens (human)
2B
(A)
17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCINnon-polymer616.71Chemie (KOS)
3C, D
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.22Chemie (MPD)
4E, F
(A)
ACETIC ACIDnon-polymer60.12Chemie (ACY)
5G
(A)
waterwater18.0277Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24122.2
Non-Polymers*Number of molecules5
Total formula weight973.2
All*Total formula weight25095.4
*Water molecules are not included.

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PDB entries from 2024-12-18

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