274D
CRYSTAL STRUCTURE OF A COVALENT DNA-DRUG ADDUCT: ANTHRAMYCIN BOUND TO C-C-A-A-C-G-T-T-G-G, AND A MOLECULAR EXPLANATION OF SPECIFICITY
Summary for 274D
Entry DOI | 10.2210/pdb274d/pdb |
Descriptor | DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)-3'), ANTHRAMYCIN (3 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, modified, dna |
Total number of polymer chains | 1 |
Total formula weight | 3360.33 |
Authors | Kopka, M.L.,Goodsell, D.S.,Baikalov, I.,Grzeskowiak, K.,Cascio, D.,Dickerson, R.E. (deposition date: 1994-04-28, release date: 1994-10-21, Last modification date: 2024-02-14) |
Primary citation | Kopka, M.L.,Goodsell, D.S.,Baikalov, I.,Grzeskowiak, K.,Cascio, D.,Dickerson, R.E. Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity. Biochemistry, 33:13593-13610, 1994 Cited by PubMed: 7947769DOI: 10.1021/bi00250a011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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