274D

CRYSTAL STRUCTURE OF A COVALENT DNA-DRUG ADDUCT: ANTHRAMYCIN BOUND TO C-C-A-A-C-G-T-T-G-G, AND A MOLECULAR EXPLANATION OF SPECIFICITY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)-3')	polymer	10	3045.0	1
2	B (A)	ANTHRAMYCIN	non-polymer		315.3	1	Chemie (ANT)
3	C (A)	water	water		18.0	22	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	3045.0
Non-Polymers*	Number of molecules	1
	Total formula weight	315.3
All*	Total formula weight	3360.3

*Water molecules are not included.