1ZYS
Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor
Summary for 1ZYS
Entry DOI | 10.2210/pdb1zys/pdb |
Related | 1NVQ 1NVR 1NVS |
Descriptor | Serine/threonine-protein kinase Chk1, pentapeptide fragment, SULFATE ION, ... (5 entities in total) |
Functional Keywords | chk1; crystal structure, signaling protein, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O14757 |
Total number of polymer chains | 2 |
Total formula weight | 32341.15 |
Authors | Stavenger, R.A.,Zhao, B.,Zhou, B.-B.S.,Brown, M.J.,Lee, D.,Holt, D.A. (deposition date: 2005-06-10, release date: 2006-06-13, Last modification date: 2024-02-14) |
Primary citation | Stavenger, R.A.,Zhao, B.,Zhou, B.-B.S.,Brown, M.J.,Lee, D.,Holt, D.A. Pyrrolo[2,3-b]pyridines Inhibit the Checkpoint Kinase Chk1 To be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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