1ZYS
Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Detector technology | AREA DETECTOR |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 44.901, 66.056, 58.135 |
| Unit cell angles | 90.00, 94.60, 90.00 |
Refinement procedure
| Resolution | 25.000 - 1.700 |
| Rwork | 0.227 |
| R-free | 0.26020 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Data reduction software | DENZO (2000) |
| Data scaling software | SCALEPACK (2000) |
| Phasing software | X-PLOR |
| Refinement software | CNS |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 25.000 |
| High resolution limit [Å] | 1.700 |
| Rmerge | 0.100 |
| Number of reflections | 36695 |
| <I/σ(I)> | 15.2 |
| Completeness [%] | 97.9 |
| Redundancy | 3.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
