1ZYS

Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor

Summary for 1ZYS

• Entry DOI: 10.2210/pdb1zys/pdb
• Related: 1NVQ 1NVR 1NVS
• Descriptor: Serine/threonine-protein kinase Chk1, pentapeptide fragment, SULFATE ION, ... (5 entities in total)
• Functional Keywords: chk1; crystal structure, signaling protein, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O14757
• Total number of polymer chains: 2
• Total formula weight: 32341.15

Authors

Stavenger, R.A.,Zhao, B.,Zhou, B.-B.S.,Brown, M.J.,Lee, D.,Holt, D.A. (deposition date: 2005-06-10, release date: 2006-06-13, Last modification date: 2024-02-14)

• Primary citation: Stavenger, R.A.,Zhao, B.,Zhou, B.-B.S.,Brown, M.J.,Lee, D.,Holt, D.A.; Pyrrolo[2,3-b]pyridines Inhibit the Checkpoint Kinase Chk1; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)