1XVP

crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO

Summary for 1XVP

• Entry DOI: 10.2210/pdb1xvp/pdb
• Related: 1XV9
• Descriptor: Retinoic acid receptor RXR-alpha, Orphan nuclear receptor NR1I3, nuclear receptor coactivator 1 isoform 1, ... (6 entities in total)
• Functional Keywords: car, rxr, citco, src1, dna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q14994 P19793
• Total number of polymer chains: 8
• Total formula weight: 117034.52

Authors

Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Moore, L.B.,Willson, T.M.,Moore, J.T. (deposition date: 2004-10-28, release date: 2004-12-28, Last modification date: 2024-02-14)

• Primary citation: Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Collins, J.L.,Moore, L.B.,Willson, T.M.,Moore, J.T.; A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.; Mol.Cell, 16:919-928, 2004; PubMed: 15610735; DOI: 10.1016/j.molcel.2004.11.042

Experimental method

X-RAY DIFFRACTION (2.6 Å)