1XVP
crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Retinoic acid receptor RXR-alpha | polymer | 236 | 26509.7 | 2 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Constitutive androstane receptor, CAR, Orphan nuclear receptor MB67 |
| 2 | B, D (B, D) | Orphan nuclear receptor NR1I3 | polymer | 246 | 28279.0 | 2 | UniProt (Q14994) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha |
| 3 | E, F, G, H (E, F, G, H) | nuclear receptor coactivator 1 isoform 1 | polymer | 13 | 1633.9 | 4 | GenBank (22538455) UniProt (by SIFTS) (Q15788) | Homo sapiens | |
| 4 | I, J (A, C) | PENTADECANOIC ACID | non-polymer | 242.4 | 2 | Chemie (F15) | |||
| 5 | K (D) | 6-(4-CHLOROPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME | non-polymer | 436.7 | 1 | Chemie (CID) | |||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
B, D: 103 - 348 (UniProt: Q14994)
| PDB | External Database | Details |
|---|---|---|
| - | Val 232 | deletion |
| - | Ser 233 | deletion |
| - | Pro 234 | deletion |
| - | Thr 235 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 116113.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 921.5 | |
| All* | Total formula weight | 117034.5 |
