crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and 5b-pregnane-3,20-dione.

Summary for 1XV9

DescriptorRetinoic acid receptor RXR-alpha, Orphan nuclear receptor NR1I3, nuclear receptor coactivator 1 isoform 1, ... (6 entities in total)
Functional Keywordscar, rxr, src1, pregnanedione, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q14994 P19793
Total number of polymer chains8
Total molecular weight116914.26
Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Moore, L.B.,Willson, T.M.,Moore, J.T. (deposition date: 2004-10-27, release date: 2004-12-28, Last modification date: 2016-11-30)
Primary citation
Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Collins, J.L.,Moore, L.B.,Willson, T.M.,Moore, J.T.
A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
Mol.Cell, 16:919-928, 2004
PubMed: 15610735 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2004.11.042
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.239323.7%4.7%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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