1XV9
crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and 5b-pregnane-3,20-dione.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Retinoic acid receptor RXR-alpha | polymer | 236 | 26509.7 | 2 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha |
| 2 | B, D (B, D) | Orphan nuclear receptor NR1I3 | polymer | 246 | 28279.0 | 2 | UniProt (Q14994) Pfam (PF00104) | Homo sapiens (human) | Constitutive androstane receptor, CAR, Orphan nuclear receptor MB67 |
| 3 | E, F, G, H (E, F, G, H) | nuclear receptor coactivator 1 isoform 1 | polymer | 13 | 1633.9 | 4 | GenBank (22538455) UniProt (by SIFTS) (Q15788) | Homo sapiens | |
| 4 | I, J (A, C) | PENTADECANOIC ACID | non-polymer | 242.4 | 2 | Chemie (F15) PubChem (13849) | |||
| 5 | K (D) | (5BETA)-PREGNANE-3,20-DIONE | non-polymer | 316.5 | 1 | Chemie (CI2) PubChem (16759982) PubChem (21039619) PubChem (176777031) PubChem (92745) PubChem (92810) PubChem (123867) PubChem (23902994) PubChem (24212165) PubChem (24779611) PubChem (25771704) PubChem (440699) PubChem (28467795) PubChem (28467804) PubChem (40768273) PubChem (40768275) PubChem (44263337) PubChem (44287287) PubChem (25771696) PubChem (57685079) PubChem (58592165) PubChem (59847734) PubChem (59859263) PubChem (70387126) PubChem (71045972) PubChem (71051776) PubChem (2825567) PubChem (7098654) PubChem (7098657) PubChem (90660571) PubChem (11877127) PubChem (11877128) PubChem (11877129) PubChem (11877130) PubChem (13581521) PubChem (13581522) PubChem (5460333) PubChem (7098656) PubChem (124422945) PubChem (7098655) PubChem (124897370) PubChem (9883423) PubChem (102018286) PubChem (130253860) PubChem (121357601) PubChem (124185417) PubChem (124426478) PubChem (124427142) PubChem (124897034) PubChem (124897035) PubChem (124897369) PubChem (124897371) PubChem (124897618) PubChem (124897619) PubChem (124897620) PubChem (129162599) PubChem (129635497) PubChem (130253852) PubChem (133688130) PubChem (134612755) PubChem (162931383) PubChem (137117762) PubChem (145130042) PubChem (153356004) PubChem (153741516) PubChem (154172615) PubChem (158050161) PubChem (144685586) PubChem (162931384) PubChem (169153737) | |||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
B, D: 103 - 348 (UniProt: Q14994)
| PDB | External Database | Details |
|---|---|---|
| - | Val 232 | deletion |
| - | Ser 233 | deletion |
| - | Pro 234 | deletion |
| - | Thr 235 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 116113.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 801.3 | |
| All* | Total formula weight | 116914.3 |
