1WBY

CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE

1WBY の概要

• エントリーDOI: 10.2210/pdb1wby/pdb
• 関連するPDBエントリー: 1BII 1BQH 1BZ9 1CD1 1CE6 1DDH 1FFN 1FFO 1FFP 1FG2 1FO0 1FZJ 1FZK 1FZM 1FZO 1G6R 1G7P 1G7Q 1HOC 1INQ 1JPF 1JPG 1JUF 1K8D 1KBG 1KJ2 1KJ3 1KPU 1KPV 1L6Q 1LD9 1LDP 1LEG 1LEK 1LK2 1MHC 1MWA 1N3N 1N59 1N5A 1NAM 1NAN 1NEZ 1OSZ 1P1Z 1P4L 1PQZ 1QLF 1QO3 1S7Q 1S7R 1S7S 1S7T 1S7U 1S7V 1S7W 1S7X 1VAC 1VAD 1WBX 1WBZ 2CKB 2MHA 2VAA 2VAB
• 分子名称: H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, BETA-2MICROGLOBULIN, INFLUENZA A PEPTIDE, ... (4 entities in total)
• 機能のキーワード: immune system, mhc class i, influenza peptide, pa224, immmune system
• 由来する生物種: MUS MUSCULUS (MOUSE); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44978.36

構造登録者

Meijers, R.,Lai, C.,Yang, Y.,Liu, J.,Zhong, W.,Wang, J.,Reinherz, E.L. (登録日: 2004-11-05, 公開日: 2005-01-19, 最終更新日: 2023-12-13)

• 主引用文献: Meijers, R.,Lai, C.,Yang, Y.,Liu, J.,Zhong, W.,Wang, J.,Reinherz, E.L.; Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance; J.Mol.Biol., 345:1099-, 2005; PubMed: 15644207; DOI: 10.1016/J.JMB.2004.11.023

実験手法

X-RAY DIFFRACTION (2.3 Å)