1W1H
Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain
Summary for 1W1H
Entry DOI | 10.2210/pdb1w1h/pdb |
Related | 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G |
Descriptor | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | pdk1, phosphoinositide dependent protein kinase 1, pkb, pleckstrin homology domain, inositol phosphate, phosphoinositide, signal transduction, pi3-kinase serine/threonine protein kinase, transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: O15530 |
Total number of polymer chains | 4 |
Total formula weight | 72593.75 |
Authors | Komander, D.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2004-06-21, release date: 2004-11-19, Last modification date: 2024-05-08) |
Primary citation | Komander, D.,Fairservice, A.,Deak, M.,Kular, G.S.,Prescott, A.R.,Downes, C.P.,Safrany, S.T.,Alessi, D.R.,Van Aalten, D.M.F. Structural Insights Into the Regulation of Pdk1 by Phosphoinositides and Inositol Phosphates Embo J., 23:3918-, 2004 Cited by PubMed: 15457207DOI: 10.1038/SJ.EMBOJ.7600379 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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