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1UU3

Structure of human PDK1 kinase domain in complex with LY333531

Summary for 1UU3
Entry DOI10.2210/pdb1uu3/pdb
Related1H1W 1OKY 1OKZ 1UU7 1UU8 1UU9 1UVR
Descriptor3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywordsprotein kinase, pkb, pdk1, inhibitor, ly333531, diabetes, cancer, transferase, serine/threonine-protein kinase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight37376.43
Authors
Komander, D.,Kular, G.S.,Schuttelkopf, A.W.,Deak, M.,Prakash, K.R.,Bain, J.,Elliot, M.,Garrido-Franco, M.,Kozikowski, A.P.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2003-12-15, release date: 2004-03-04, Last modification date: 2023-12-13)
Primary citationKomander, D.,Kular, G.S.,Schuttelkopf, A.W.,Deak, M.,Prakash, K.R.,Bain, J.,Elliot, M.,Garrido-Franco, M.,Kozikowski, A.P.,Alessi, D.R.,Van Aalten, D.M.F.
Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1
Structure, 12:215-, 2004
Cited by
PubMed: 14962382
DOI: 10.1016/J.STR.2004.01.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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