Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A1367 |
Chain | Residue |
A | LYS76 |
A | ARG131 |
A | THR148 |
A | PHE149 |
A | GLN150 |
A | HOH2274 |
A | HOH2275 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A1368 |
Chain | Residue |
A | SER160 |
A | GLN220 |
A | GOL1359 |
A | HOH2161 |
A | HOH2276 |
A | LYS144 |
A | TYR146 |
site_id | AC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A1369 |
Chain | Residue |
A | ARG106 |
A | PRO140 |
A | LYS144 |
A | HIS351 |
A | GOL1359 |
A | SO41373 |
A | HOH2277 |
A | HOH2278 |
A | HOH2279 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A1370 |
Chain | Residue |
A | LYS83 |
A | VAL345 |
A | THR346 |
A | TRP347 |
A | GLU348 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A1371 |
Chain | Residue |
A | GLY91 |
A | SER92 |
A | PHE93 |
A | SER94 |
A | GOL1360 |
A | LY41374 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A1372 |
Chain | Residue |
A | ARG75 |
A | ARG136 |
A | LYS199 |
site_id | AC7 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A1373 |
Chain | Residue |
A | ARG106 |
A | GLU107 |
A | HIS351 |
A | GLN352 |
A | GOL1359 |
A | SO41369 |
A | HOH2042 |
A | HOH2281 |
A | HOH2282 |
site_id | AC8 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE LY4 A1374 |
Chain | Residue |
A | LEU88 |
A | GLY89 |
A | ALA109 |
A | LYS111 |
A | GLU130 |
A | VAL143 |
A | LEU159 |
A | SER160 |
A | TYR161 |
A | ALA162 |
A | GLY165 |
A | GLU166 |
A | GLU209 |
A | ASN210 |
A | LEU212 |
A | THR222 |
A | ASP223 |
A | GOL1366 |
A | SO41371 |
site_id | AC9 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A1359 |
Chain | Residue |
A | ARG106 |
A | GLU107 |
A | TYR108 |
A | TYR161 |
A | SO41368 |
A | SO41369 |
A | SO41373 |
A | HOH2104 |
A | HOH2278 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A1360 |
Chain | Residue |
A | LYS111 |
A | LEU113 |
A | TYR126 |
A | VAL127 |
A | GLU130 |
A | SO41371 |
site_id | BC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A1361 |
Chain | Residue |
A | PRO79 |
A | LYS154 |
A | TYR156 |
A | GLU328 |
A | GLU331 |
A | GLY332 |
A | HOH2268 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A1362 |
Chain | Residue |
A | LYS76 |
A | PHE147 |
A | THR148 |
A | HOH2092 |
site_id | BC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A1363 |
Chain | Residue |
A | LEU297 |
A | TYR299 |
A | PHE301 |
site_id | BC5 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A1364 |
Chain | Residue |
A | TRP347 |
A | GLU348 |
A | ASN349 |
A | LEU350 |
A | HIS351 |
A | ALA103 |
A | THR104 |
A | SER105 |
A | HIS139 |
A | SER191 |
site_id | BC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A1365 |
Chain | Residue |
A | PHE82 |
A | LYS83 |
A | PHE84 |
A | GLU194 |
A | GLY334 |
A | LYS337 |
A | HOH2269 |
A | HOH2270 |
A | HOH2273 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A1366 |
Chain | Residue |
A | GLY89 |
A | GLU90 |
A | LY41374 |
A | HOH2021 |
A | HOH2109 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGSFSTVVlArelatsre..........YAIK |
Chain | Residue | Details |
A | LEU88-LYS111 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpeNILL |
Chain | Residue | Details |
A | ILE201-LEU213 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP205 | |
Chain | Residue | Details |
A | SER92 | |
A | LYS111 | |
A | SER160 | |
A | GLU166 | |
A | ASP223 | |
Chain | Residue | Details |
A | GLU209 | |
Chain | Residue | Details |
A | SEP241 | |
Chain | Residue | Details |
A | LYS304 | |
Chain | Residue | Details |
A | THR354 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | GLU209 | |
A | ASP205 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | LYS207 | |
A | ASP205 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | LYS207 | |
A | THR245 | |
A | ASP205 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | LYS207 | |
A | ASN210 | |
A | ASP205 | |