1UVR
Structure of human PDK1 kinase domain in complex with BIM-8
Summary for 1UVR
Entry DOI | 10.2210/pdb1uvr/pdb |
Related | 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 |
Descriptor | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | protein kinase, pkb, pdk1, inhibitor, ly333531, bisindolyl maleimide, bim-8, diabetes, cancer, transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 34971.93 |
Authors | Komander, D.,Garrido-Franco, M.,Kular, G.S.,Schuttelkopf, A.W.,Deak, M.,Prakash, K.R.,Bain, J.,Elliot, M.,Kozikowski, A.P.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2004-01-22, release date: 2004-03-04, Last modification date: 2023-12-13) |
Primary citation | Komander, D.,Kular, G.S.,Schuttelkopf, A.W.,Deak, M.,Prakash, K.R.,Bain, J.,Elliot, M.,Garrido-Franco, M.,Kozikowski, A.P.,Alessi, D.R.,Van Aalten, D.M.F. Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12:215-, 2004 Cited by PubMed: 14962382DOI: 10.1016/J.STR.2004.01.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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