1UU8

Structure of human PDK1 kinase domain in complex with BIM-1

1UU8 の概要

関連するPDBエントリー1H1W 1OKY 1OKZ 1UU3 1UU7 1UU9 1UVR
分子名称3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total)
機能のキーワードprotein kinase, pkb, pdk1, inhibitor, ly333531, bisindolyl maleimide, bim-1, diabetes, cancer, transferase, serine/threonine-protein kinase
由来する生物種HOMO SAPIENS (HUMAN)
ポリマー鎖数1
分子量合計36844.02
構造登録者
主引用文献
Komander, D.,Kular, G.S.,Schuttelkopf, A.W.,Deak, M.,Prakash, K.R.,Bain, J.,Elliot, M.,Garrido-Franco, M.,Kozikowski, A.P.,Alessi, D.R.,Van Aalten, D.M.F.
Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1
Structure, 12:215-, 2004
PubMed: 14962382 (主引用文献が同じPDBエントリー)
DOI: 10.1016/J.STR.2004.01.005
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.5 Å)
?

構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.249110 3.0% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード