1UKL
Crystal structure of Importin-beta and SREBP-2 complex
Summary for 1UKL
Entry DOI | 10.2210/pdb1ukl/pdb |
Descriptor | Importin beta-1 subunit, Sterol regulatory element binding protein-2 (2 entities in total) |
Functional Keywords | transcription factor, nuclear transport factor, heat repeat, helix-loop-helix leucine zipper, protein transport-dna binding protein complex, protein transport/dna binding protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cytoplasm (By similarity): P70168 Endoplasmic reticulum membrane; Multi-pass membrane protein. Processed sterol regulatory element-binding protein 2: Nucleus: Q12772 |
Total number of polymer chains | 6 |
Total formula weight | 223652.20 |
Authors | Lee, S.J.,Sekimoto, T.,Yamashita, E.,Nagoshi, E.,Nakagawa, A.,Imamoto, N.,Yoshimura, M.,Sakai, H.,Tsukihara, T.,Yoneda, Y. (deposition date: 2003-08-26, release date: 2003-12-09, Last modification date: 2023-11-15) |
Primary citation | Lee, S.J.,Sekimoto, T.,Yamashita, E.,Nagoshi, E.,Nakagawa, A.,Imamoto, N.,Yoshimura, M.,Sakai, H.,Chong, K.T.,Tsukihara, T.,Yoneda, Y. The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor Science, 302:1571-1575, 2003 Cited by PubMed: 14645851DOI: 10.1126/science.1088372 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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