1UKL

Crystal structure of Importin-beta and SREBP-2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Importin beta-1 subunit	polymer	876	97271.8	2	UniProt (P70168) Pfam (PF03810) Pfam (PF13513)	Mus musculus (house mouse)	Importin-beta
2	C, D, E, F (C, D, E, F)	Sterol regulatory element binding protein-2	polymer	61	7277.2	4	UniProt (Q12772) Pfam (PF00010)	Homo sapiens (human)	SREBP-2

Sequence modifications

A, B: 1 - 876 (UniProt: P70168)

PDB	External Database	Details
Met 388	Val 388	SEE REMARK 999

C, D, E, F: 343 - 403 (UniProt: Q12772)

PDB	External Database	Details
Mse 358	Met 358	modified residue
Mse 364	Met 364	modified residue
Mse 392	Met 392	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	223652.2
All*	Total formula weight	223652.2

*Water molecules are not included.