1TNZ

Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a RRCVLL Peptide Derived from Cdc42 splice isoform-2

1TNZ の概要

• エントリーDOI: 10.2210/pdb1tnz/pdb
• 関連するPDBエントリー: 1D8D 1N4P 1N4Q 1QBQ 1TN6 1TN7 1TN8 1TNB 1TNO 1TNU 1TNY
• 分子名称: geranylgeranyltransferase type I alpha subunit, Geranylgeranyl transferase type I beta subunit, Cell division control protein 42 homolog (Cdc42), ... (8 entities in total)
• 機能のキーワード: ggtase-i, geranylgeranyltransferase type-i, geranylgeranyl transferase, prenyltransferase, caax, cdc42, lipid modification, prenylation, substrate selectivity, transferase
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 527366.61

構造登録者

Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. (登録日: 2004-06-11, 公開日: 2004-11-02, 最終更新日: 2023-08-23)

• 主引用文献: Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S.; Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.; J.Mol.Biol., 343:417-433, 2004; PubMed: 15451670; DOI: 10.1016/j.jmb.2004.08.056

実験手法

X-RAY DIFFRACTION (2.9 Å)