1TNY

Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a FREKKFFCAIL Peptide Derived from the Heterotrimeric G Protein Gamma-2 Subunit

1TNY の概要

• エントリーDOI: 10.2210/pdb1tny/pdb
• 関連するPDBエントリー: 1D8D 1N4P 1N4Q 1QBQ 1TN6 1TN7 1TN8 1TNB 1TNO 1TNU 1TNZ
• 分子名称: geranylgeranyltransferase type I alpha subunit, Geranylgeranyl transferase type I beta subunit, guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, ... (8 entities in total)
• 機能のキーワード: ggtase-i, geranylgeranyltransferase type-i, geranylgeranyl transferase, prenyltransferase, caax, heterotrimeric g protein, lipid modification, prenylation, substrate selectivity, transferase
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 531335.46

構造登録者

S Reid, T.,Terry, K.L.,Casey, P.J.,Beese, L.S. (登録日: 2004-06-11, 公開日: 2004-11-02, 最終更新日: 2023-08-23)

• 主引用文献: Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S.; Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.; J.Mol.Biol., 343:417-433, 2004; PubMed: 15451670; DOI: 10.1016/j.jmb.2004.08.056

実験手法

X-RAY DIFFRACTION (2.7 Å)